BIOINFORMATICIAN

Descripción The Barcelona Institute for Global Health (ISGlobal) is a cutting-edge institute addressing global public health challenges through research, translation into policy and education.
ISGlobal has a broad portfolio in communicable and non-communicable diseases including environmental and climate determinants, and applies a multidisciplinary scientific approach ranging from the molecular to the population level.
Research is organized in the following main areas, Malaria and other Infectious Diseases, Maternal, Child and Reproductive Health, Urban Health, Child and Environmental health, and Climate & Non-Communicable Diseases.
ISGlobal is accredited with the Severo Ochoa distinction, a seal of excellence of the Spanish Science Ministry.
Lugar Barcelona, Campus Clinic-CEK WHAT WE ARE LOOKING FOR ISGlobal is seeking a Master’s level researcher in bioinformatics and data science to work on the malaria research projects performed by the Malaria Immunology Group.
The overall goals are to identify molecular signatures correlating and predicting vaccine immunogenicity and protection against and understand the mechanisms and mediators of protective immunity induced by infection and vaccines using single-cell RNAseq and CITE-Seq methods and multidimensional clinical, epidemiological, immunological and molecular data.
ABOUT THE POSITION ISGlobal is seeking a researcher in bioinformatics to work on the project “Unravelling the heterogeneity and function of monocytes in vaccination and immunity to malaria (VaMonoS)”, project PIDOB-I00 funded by the Ministry of Science (MCIN/AEI/// FEDER, UE).
The aim of this project is to decipher the molecular, phenotypic and functional profiles of monocyte subsets associated with vaccine immunogenicity and induced protection.
Ultimately, the goal of this project is to improve the health of people, particularly those responding poorly to vaccines, through the generation of novel knowledge on monocytes immunology.
SPECIFIC REQUIREMENTS Bioinformatics expertise in omics analysis is essential  Previous expertise in malaria and immunology research  Knowledge of predictive analysis, modeling and machine learning is required to analyze complex immunological data sets Advanced bioinformatics skills and programming, preferably with R Experience with database management software including R Experience/knowledge in analysing complex multidimensional data using machine learning methods Motivated researcher capable of setting and meeting deadlines and delivering research outputs to the required standard   KEY RESPONSIBILITIES Management and analysis of data generated in single-cell RNAseq, CITE-seq and ATAC-Seq experiments in relation to malaria vaccination and infection.
Integration of single-cell data with immunological, epidemiological and clinical datasets In addition, management and analysis of other OMIC data in relation to malaria immunity.
SPECIFIC DUTIES Design, implement, manage relational databases Contribute to developing robust, standardized bioinformatic pipelines for single-cell techniques.
scRNA-seq and CITE-Seq Perform the analysis of single-cell data generated in the group and integrate it with immunological, epidemiological and clinical data.
Establish general quality controls, standards and good practices to ensure quality and reproducibility Provide training and support to the teams for the execution and analysis of specific experiments Carry out data cleaning and quality control,  Document and archive all data for easy use in future research Conduct statistical analyses of the data using specialised bioinformatics software for immunology studies Prepare data reports and manuscripts AUXILIAR TASKS This job description reflects the present requirements of the post but may evolve at any time in the future as duties and responsibilities change and/or develop providing there is appropriate consultation with the post-holder.
This job description is not a definitive or exhaustive list of responsibilities but identifies the key responsibilities and tasks of the post holder.
The specific objectives of the post holder will be subject to review as part of the individual professional assessment  process.
SKILLS Outstanding organizational and team-working skills (yet capable of working independently).
Responsible, flexible and with problem solving skills.
Eager to learn, proactive and with great initiative.
Capability of setting and meeting deadlines.
Demonstrable adaptability and flexibility to adapt positively to changes.
Availability to travel as required by project activities.
The post holder will adhere to ISGlobal principles contained in People management policy, including Equity, diversity and health safety.
The post holder will respect, and accountable to ensure ISGlobal policies and procedures.
LANGUAGE LEVEL Proficiency in English (written and spoken)  Knowledge of Spanish and/or Catalan would be an asset.
CONDITIONS Duration.
12 months (with the possibility of extension pending successful evaluations).
Starting date.
October Contract.
Full-time.
Salary Range.
According to experience and internal salary scale HOW TO APPLY Applicants must fill in the request form and include the following code reference position.
Bioinfo_Immuno_Sep24, attach the CV and a Cover Letter.
Each attached document must be named with the candidate name and surname.
The receipt of applications will be open until Applications will be accepted until CET of the closing date.
Only the applications submitted through the request form will be considered.
Only shortlisted candidates will be contacted.
The interviews could be placed during the reception candidatures period.
Diverse candidatures are encouraged, that includes.
gender, race, ethnicity, religion, age, sexual orientation, physical abilities, and political views.
SELECTION PROCESS The selection process is designed in two phases.
1- Interview phase of a technical nature, with the team that requires the incorporation.
To assess the person's skills and CV.
2 - Meeting with HR with the finalist(s) to finish assessing the profile and discuss contractual and institutional issues.
If needed any technical test could be pass.
A Psychological Competency Evaluation Test will be required for the structural or transversal positions.
In accordance with the OTM-R principles, a gender-balanced recruitment panel is formed for every vacancy at the beginning of the process.
After reviewing the content of the applications, the panel will start the interviews, with at least one technical and one administrative interview.
A profile questionnaire as well as a technical exercise may be required during the process.
In ISGlobal we are committed to maintaining and developing a work environment in which the values and principles of our organization are respected and equal opportunities between women and men be promoted in each of the areas in which we operate, not tolerating discrimination based on criteria such as age, gender, marital status, race, ethnicity, functional diversity, political leanings, religion, sexual orientation, gender identity or gender expression.
ISGlobal supports the initiative #ScienceforUkraine.
Therefore, to sustain Ukraine’s presence in the European Research Area and international scholarly community, candidates from Ukraine on all levels of scholarly career are welcome.
students, PhD candidates, early career researchers and senior scholars.
We confirm our commitment towards the value of the diversity of our staff and student population and seek to promote peace, equity, diversity and inclusion as essential elements in contribution to improving health worldwide.