SCIENTIST ADVANCED THERAPIES

J&J Innovative Medicines s recruiting for an Associate Scientist Process Development, Advanced Therapies located in Leiden.
JnJ Innovative Medicines is committed to developing outstanding medication for some of the world’s most life-threatening diseases.
In Leiden, we have a workforce of 350 scientists and support staff.
We partner with leading experts, academic and clinical institutions and other pharmaceutical companies for the early development of production processes.
In our organization entrepreneurial people are working in a high-performance culture in which innovation and a 'can do' state of mind are the central points.
To strengthen our team, we are continuously looking for enthusiastic people who have the ambition to develop themselves and the way we work.
The API (Active Pharmaceutical Ingredient) Process Development department is responsible for the development of scalable, pharmaceutical-grade production processes.
Our focus is early development of process steps ranging from (mammalian) cell culturing, up to and including purification.
We apply our knowledge to a diverse panel of modalities in the Advanced Therapies domain.
Novel technologies are used to ensure that the processes are safe, reliable, scalable, and cost-efficient.
The developed production processes are transferred into GMP production facilities to produce clinical batches and scaled-up for commercial production.
All activities are performed in close collaboration with other departments.
Alignment with our GMP pilot plant is of particular importance in this respect.
We are looking for a motivated Associate Scientist within the field of process development.
Under limited supervision, but as part of a team you will plan, prepare and execute scientific studies.
Typical unit operations include cell culture (both bacterial and mammalian), filtration, chromatography and UF/DF.
Experiments may be performed on pilot scale and/or in reduced-scale models.
You work accurately and you are a team player with excellent communicational skills.
You are able to lead and define studies, co-write study plans and reports.
You can collect and interpret the data retrieved from the experiments.
This position requires full-time on-site presence.
As J&J, we aim to be an inclusive company, feel free to indicate your needs during an interview in order to be able to implement your role and responsibilities.
Job description We are looking for a motivated Associate Scientist of the Process Development department.
In this role, you ensure a smooth operation of the activities of the team.
This includes, but is not limited to.
Working with the team to ensuring smooth and timely execution of experiments on lab & pilot scale to meet project demands, this includes managing ordering of raw materials, equipment, planning resources and sample analysis Leading and defining studies and writing related study plans and study reports Performing experiments at lab scale and pilot scale Identify improvements and take the initiative to execute these identified opportunities compromising the execution of scientific experiments Ensure and maintain the proper EHS&S and Quality standard of the team Support cross departmental collaboration with other departments (GMP pilot plant and Commercial production facility), ensuring optimal (operational) knowledge sharing and assuring aligned process execution on all scales Qualifications Qualifications BSc/MSc in chemical engineering, microbiology or similar life science related field with minimum of 3 years of hands-on operational experience (lab and pilot scale) Experience with defining studies, writing study plans and reports Proven project lead skills Knowledge of and experience of working with BSL-levels Ability to work under close supervision in the delivery of assigned research and/or analytic tasks and activities Independently perform routine and complex process development operations, including cell culture, chromatography and TFF.
Ability to troubleshoot technical issues and implement solutions.
Meticulous attention to detail and accuracy in data recording.
Affinity with data management and automated dataflows Excellent teamwork and communication skills.
The most important competences for this position are.
Pragmatic and independent Demonstrated communication capabilities and the ability to lead by example Build and sustain a safe environment in the lab Troubleshooting and decision making in various activities in the lab Quality, efficiency, accuracy and reliability of work Affinity with continuous innovations needed to improve the efficiency of business processes Experience with automation systems like BSI, eLN and data-structure